My research interests focus on lipid homeostasis, understanding how cells produce and store lipids depending on their needs. I primarily study lipid dynamics of the endoplasmic reticulum which is the hub of lipid synthesis and storage in the cell. 在实验室里, we use the power of yeast to develop genetic screens to identify genes playing key roles in these processes. Follow up investigations of these genes are performed both in yeast and human cells using molecular/cellular biology, biochemistry and fluorescent microscopy techniques.

Becuwe米, 债券LM, 平托AFM, 博兰年代, Mejhert N, 艾略特SD, Cicconet米, 格雷厄姆毫米, 刘XN, Ilkayeva O, Saghatelian一, 沃尔特TC, 小Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. Journal of Cell 生物logy. (2020) Oct 5;219(10):e202006111. doi: 10.1172 / JCI140494.

Becuwe米 *, Gluchowski NL*, 沃尔特TC, 小Farese RV. Lipid droplets and liver diseases: from basic biology to clinical implications. Nature Review Gastroenterology and Hepatology. (2017) 6月,14 (6):343 - 355. doi: 10.1038. * Co-First作者.

Becuwe米 和Leon S. – Integrated control of transporter endocytosis and recycling by the Rod1-Rsp5 ubiquitylation complex. Elife (2014). 11月7日,3. doi: 10.7554

Becuwe米, Herrador A, Haguenauer-tsapis R, 文森特·阿 和Leon S. – Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family. (邀请审查) 生物chemical Research International (2012). 2012:242764.

Becuwe米, 维埃拉N, 劳拉D, Gomes-Rezende J, Soares-Cunha C, 有格的米, Haguenauer-Tsapis R, 文森特·阿, Paiva年代, 莱昂年代. – A molecular switch on a yeast arrestin-like protein relays glucose signaling to transporter endocytosis. Journal of Cell 生物logy (2012) 1月23日,196 (2):247 - 59.

选择 在部分中 “焦点” 由米奇 莱斯利(2012) Spare the Rod1, spoil transporter endocytosis. Journal of Cell 生物logy 196, 181

Joron M, Frezal L, Jones RT, Chamberlain NL, Lee SF, Haag CR, Whibley A, Becuwe米, 巴克斯特西南, 弗格森L, 威尔金森PA, 萨拉查C, 戴维森C, 克拉克R, 鹌鹑马, 比斯利H, Glithero R, 劳埃德·C, 西姆斯年代, 琼斯MC, 罗杰斯J, Jiggins CD, ffrench-Constant猕. – Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mmicry. 自然(2011) Aug 14;477(7363):203-6.

• Harvard College Certificate of Distinction in Teaching Fall 2020, 2021年春季, 2021年秋季, 2022年春季
• Doty-Losick Prize for Excellent Service - Department of Molecular and Cellular 生物logy – Harvard university (2021).
• Jane Coffin Childs postdoctoral fellowship (2015-2018)
• Fellowship from the Philippe Foundation (2016-2017)
• European Molecular 生物logy Organization Long term fellowship (2015)
• Fellowship from the French Research Ministry (2010-2013)