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Institutional Review Board
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Collaborative Research
Whether additional IRB requirements apply to multisite /collaborative research often depends on whether an external site or personnel are engaged in human subjects research. bet亚洲365欢迎投注 relies on the federal guidance on engagement in research to determine whether IRB oversight for external sites or personnel is required and, 如果是这样的话, what IRB reliance mechanism to use to ensure oversight is in place. Researchers are encouraged to review the resources below to help determine what additional requirements may apply to their study and to contact the IRB的椅子person with any questions.
Federally-funded cooperative (i.e, "multi-site") human research studies are required per the Common Rule (45 CFR 46.114)(link is external) to utilize a single IRB-of-Record (sIRB) to streamline the review process for human participant protections and to avoid duplicate review by an institutional review board at each site.
在sIRB模型下, an IRB at one of the collaborating institutions agrees to provide IRB oversight for all participating institutions via an authorization agreement (a.k.a. "reliance" or "collaborative" agreement) or a commercial IRB is contracted to provide the oversight functions for the project. These agreements/contracts document the respective authority, 角色, 责任, and communication plans among the IRB-of-Record (i.e., the "reviewing IRB") and the institutions relying on that IRB (i.e., "relying site" and "relying IRB") for project oversight.
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Marist IRB记录
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What is a multisite study?
From an IRB perspective, multisite research includes projects or studies that involve collaboration with sites or individuals with not a Marist employee or student. Some examples of multisite and collaborative research include:
An investigator with a Marist appointment is conducting a study involving other institutions.
Marist investigator conducting a study at a community-based site with a community partners.
Marist investigator sharing identifiable or coded data/images/specimens collected for a study with researchers at another university or institution